natural plant extracts - backed by research - promoting holistic health
Dementia: Australia's Leading Cause of Death 2024
Dementia has surpassed cardiovascular disease as the leading cause of death in Australia in 2024. This trend highlights the urgent need for preventive measures to safeguard brain health. Discover h...
ANTI-AGEINGCARDIOVASCULAR HEALTHLONGEVITYMETABOLIC HEALTHBRAIN HEALTHINFLAMMATIONCELLULAR HEALTH
AlexanderJ
1/21/20252 min read


The Science Behind Neurodegeneration
Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and other forms of dementia, are linked to oxidative stress and mitochondrial dysfunction. These factors contribute to the progressive loss of structure and function in brain cells, eventually leading to cognitive decline and memory loss. As we age, the body’s natural production of antioxidants and vital molecules like GG decreases, leaving our brain cells vulnerable to damage.
Annatto Tocotrienol - A Potent Antioxidant
Annatto tocotrienol, a form of vitamin E extracted from the seeds of the annatto plant, is a powerful antioxidant. Unlike the more common tocopherols, tocotrienols have a unique molecular structure that allows them to penetrate fatty tissues like the brain more effectively. This enables tocotrienols to:
Combat Oxidative Stress: By neutralizing harmful free radicals, tocotrienols protect brain cells from damage.
Reduce Neuroinflammation: Chronic inflammation in the brain is a hallmark of Alzheimer’s and other neurodegenerative diseases. Tocotrienols have been shown to lower markers of inflammation.
Prevent Cell Death: Tocotrienols inhibit the enzyme 5-lipoxygenase, which plays a role in cell death pathways linked to neurodegeneration.
Annatto GG - The Cellular Energizer
Geranylgeraniol (GG) is a vital molecule required for cellular energy production and repair. Found naturally in the body, GG levels decline with age, compromising the brain’s ability to maintain healthy cell function. Supplementing with annatto-derived GG can:
Boost Mitochondrial Function: Mitochondria are the energy powerhouses of cells. GG supports mitochondrial health, ensuring brain cells have the energy needed for optimal function.
Enhance Protein Synthesis: GG is critical for synthesizing proteins that repair and maintain cell structure.
Support Myelin Production: Myelin is the protective sheath around nerve fibers, essential for efficient neural communication. GG aids in its production, preserving cognitive abilities.
Synergy Between Tocotrienol and GG
When combined, annatto tocotrienol and GG create a powerful synergy that enhances their individual benefits:
Comprehensive Cellular Protection: Tocotrienol defends against oxidative damage, while GG promotes repair and regeneration.
Improved Cognitive Function: Together, they support memory, focus, and overall brain performance.
Reduced Risk of Neurodegenerative Diseases: By addressing the root causes of neurodegeneration, this duo offers a preventive strategy to protect brain health.
Evidence from Research
Numerous studies highlight the neuroprotective benefits of tocotrienols and GG:
Tocotrienols and Brain Health: Research published in the Journal of Alzheimer’s Disease found that tocotrienols reduced oxidative stress and improved cognitive performance in animal models.
Anti-Inflammatory Effects: A study in Nutrition Reviews demonstrated that tocotrienols lower levels of pro-inflammatory cytokines linked to Alzheimer’s disease.
GG and Cellular Energy: A review in the Journal of Molecular Neuroscience emphasized GG’s role in enhancing mitochondrial function and preventing age-related cellular decline.
Why Choose Annatto-Derived Tocotrienol and GG?
Annatto is the only natural source of pure delta- and gamma-tocotrienols, the most bioactive forms of vitamin E. Similarly, annatto-derived GG is free from contaminants and provides optimal bioavailability. Together, they offer a safe, natural, and effective solution for supporting brain health.
Recommendations for Use
For individuals focused on preventing cognitive decline or supporting brain function, consider the following daily regimen:
Preventive Dose: 125 mg of annatto tocotrienol and 75 mg of GG.
Therapeutic Dose: 300 mg of annatto tocotrienol and 150 mg of GG for those with a higher risk of neurodegeneration.
Take Action Today
Don’t wait for symptoms to appear. Protect your brain health proactively with annatto tocotrienol and GG. These scientifically backed supplements offer a natural way to combat the leading causes of neurodegeneration, helping you maintain cognitive vitality as you age.